Imagine living with a condition where your body and mind seem to be at war with each other, gradually robbing you of control over your movements, thoughts, and emotions. This is the reality for individuals and families affected by Huntington’s disease (HD). In this blog post, we’ll explore the intricacies of Huntington’s disease, from its genetic roots to its impact on individuals and their loved ones.

What is Huntington’s Disease?

Huntington’s disease is a hereditary neurodegenerative disorder characterized by progressive motor, cognitive, and psychiatric symptoms. It typically begins to manifest in adulthood, usually between the ages of 30 and 50, although onset can occur at any age. HD is caused by a mutation in the HTT gene, leading to the production of a toxic protein called mutant huntingtin. This protein disrupts normal cellular function, particularly in the brain, leading to the gradual deterioration of nerve cells.

Symptoms of Huntington’s Disease

The symptoms of Huntington’s disease can vary widely among affected individuals, both in terms of the type and severity of symptoms and the age of onset. Motor symptoms often emerge first and may include involuntary movements known as chorea, as well as difficulties with coordination, balance, and swallowing. Cognitive symptoms may include impairments in memory, reasoning, and judgment, while psychiatric symptoms can manifest as depression, anxiety, irritability, and even psychosis.